Before Louis Pasteur, it was believed that miasma (bad air) caused disease and that spontaneous generation is the process in which decaying matter creates living organisms such as maggots and another insect to be the way in which that decaying matter would end up with living organisms on it.
In 1861 Louis Pasteur discovered microbes after performing experiments for the alcohol industry to find out why the wines and beers were going bad he could not have done this without the new technologies of the time such as the powerful electron microscopes.
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After Louis Pasteur discovered germs and published his works another scientist named Robert Koch began to look at whether there was a link between these tiny microorganisms and disease in humans so to start with he had to be able to differentiate between different microbes so in turn created “Bacteriology” this is the system in which tells one germ from another after doing this he was able to test drugs and other materials to find out what killed each bacteria.
After Pasteur found out about this he set about to use this to find a vaccine for chicken cholera, in my opinion, this was only because Pasteur was French and German and at this time there was the Franco-Prussian war was upon them.
After experimentation with chickens, Pasteur and his lab partner found out that if you inject a weakened sample of chicken cholera in the chickens they become immune to the infection after this Pasteur also discovered a vaccine for tuberculosis.
After having studied both of these great scientists I cannot come to a decision about who is more important in the history of medicine as if pateurs work on the germ theory hadn’t have been done Koch would not have worked to make bacteriology but if Koch had not done this pasture would not have gone back to find a vaccine for chicken cholera.
After having read about both these men’s work Paul Ehlich began to look for chemicals, which could work as synthetic anti-bodies which by this time have been worked out to be the bodies defences and only attack certain chemicals in the body
After years of work and experimenting with over 600 chemicals none worked until his results were checked again and appeared to have 1 working chemical. Chemical 606 was first used in1911 under the trade name of salvasan 606 this was to become the first magic bullet which is a turning point in the history of medicine because now more scientific research begins to be made to finding more magic bullets but no more are found until the discovery of prontasil in 1932 just before world war 1.
In conclusion to looking at all three of these historic figures, I still cannot make a decision on which one is the most significant in the history of medicine and cannot make a solid decision on who had the biggest impact on the history of medicine and why.
Because on the one hand if Pasteur did not discover germs and Publish his germ theory no other scientists could have carried on research into germs and find vaccines and how to kill germs there for Pasteur should be the most significant but if Koch wouldn’t have done his work on microbe we wouldn’t be able to differentiate between microorganism stopping us from developing vaccines so no matter who you talk about everyone made a contribution and without any of them we could not be where we are today.
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